Conference "Post-Genome Methods of Analysis in Biology and Laboratory and Clinical Medicine"

The conference will take place on October 29 - November 1, 2014 in Kazan. The organizers are Kazan Federal University, Ministry of Industry and Trade, Ministry of Education and Science of Russian Federation and Russian Foundation for Basic Research. The program includes over 100 talks. Bioinformatics and metagenomics are among the topics.

Article published: Rural and urban microbiota: to be or not to be?

Our article was published in Gut Microbes journal.

Rural and urban microbiota: to be or not to be?

Alexander V. Tyakht, Dmitry G. Alexeev, Anna S. Popenko, Elena S. Kostryukova & Vadim M. Govorun   

Gut Microbes 5:3, Article number: 28685 | doi: 10.4161/gmic.28685

Submitted 28 Jan 2014 | Revised 21 Mar 2014 | Accepted 27 Mar 2014 | Published Online 1 Apr 2014


Article published: Human gut microbiota community structures in urban and rural populations in Russia

Our article was published in Nature Communications journal.

Temporal evolution of gut microbiota during chemotherapy in acute leukemia pediatric patients

At the International Human Microbiome Congress (IHMC-2013) in Hangzhou, China, we presented a poster with the result of our pilot project. Click here to download it (PDF).

Article published: MALINA: a web service for visual analytics of human gut microbiota whole-genome metagenomic reads

Our software article was published in Source Code for Biology and Medicine journal. 

MALINA: a web service for visual analytics of human gut microbiota whole-genome metagenomic reads

Alexander V Tyakht, Anna S Popenko, Maxim S Belenikin, Ilya A Altukhov, Alexander V Pavlenko, Elena S Kostryukova, Oksana V Selezneva, Andrei K Larin, Irina Y Karpova and Dmitry G Alexeev

Source Code for Biology and Medicine 2012, 7:13 doi:10.1186/1751-0473-7-13
Published: 7 December 2012

Novel community types revealed by continent-wide human gut metagenomic study

At ECCB'12 in Basel, Switzerland, we presented a poster with our findings. Click here to download (PDF, 7 Mb).

Examining composition of Russian human gut microbiota by assessing relative abundance of functional and taxonomical units

Russian Metagenomic Project is an initiative lead by a consortium of Russian scientific and medical institutes targeting study of human gut microbiome of Russian population. During Phase I of project, fecal metagenomic samples of 132 subjects were sequenced on ABI SOLiD sequencer and analyzed bioinfor-matically.The composition was derived by assessment of taxonomic and functional relative abundance, allowing linking with various medical and ethno-geographical factors.

MALINA —whole-genome metagenomic reads analysis

Huge volume of whole-genome metagenomic samples in repositories keeps growing at increasing pace. In community of researchers, there is a need for robust data analysis tools that allow efficient description of composition, classification and clustering coupled with comprehensive visualization of results Particularly, human gut microbiome is one of extensively studied topics in metagenomic research.We developed a software pipeline for bioinformatic analysis of metagenomic data obtained from human gut microbiota sequencing currently available as a free web service MALINA.

First batch of samples in Russian metagenomic project processed

In December 2010, the Genomic Center of RIPCM FMBA of Russia obtained results of sequencing for the first ten samples of human gut microbiota. Their basic taxonomic and functional composition has been examined. January brought an extra sequencing validation run that confirmed the results of the first run and allowed to choose detection threshold for various bacterial species in a sample.